Genetic Tweaks in Astrocytes Could Be Key to Alzheimer's …
WEB2 days ago · When astrocytes in the brains of mice were genetically modified to trigger their autophagy forms, damage to neurons caused by Alzheimer's-like symptoms reversed and cognitive functions and memory improved, the researchers discovered. Two key genes involved, called SQSTM1 and LC3B, produce a protein that helps eat up …
Autophagy pathway in astrocytes raises possibility of Alzheimer's ...
WEB3 days ago · Credit: Korea Institute of Science and Technology. A research team has uncovered a new mechanism involving astrocytes for treating Alzheimer's disease (AD) and proposed a novel therapeutic target ...
Astrocyte - Latest research and news - Nature
WEB5 days ago · Astrocyte articles from across Nature Portfolio. Astrocytes are the largest and most prevalent type of glial cell in the central nervous system. Astrocytes contribute to formation of the...
Astrocytes study identifies a new therapeutic target for …
WEBSep 23, 2024 · The study found that damaged astrocytes in Alzheimer's disease have less energy production and generate more stress on the mitochondria. The work is published in the journal Molecular Psychiatry.
New insights into astrocytes offer hope for Alzheimer's treatment
WEB3 days ago · Dr. Ryu and Dr. Suhyun Kim (the first author) commented, " Our findings show that astrocytic autophagy restores neuronal damage and cognitive functions in the dementia brain. We hope this study ...
Astrocytes are enablers of brain metastases - Nature Cell Biology
WEB4 days ago · A new study reveals a previously unknown type of astrocyte–tumour cell interaction. Brain metastases are a fatal complication of advanced cancers, most commonly originating from lung, skin ...
Astrocyte cells in the brain have immune memory - Nature
WEBMar 20, 2024 · Astrocyte cells in the brain have immune memory. The central nervous system’s astrocyte cells respond to injury and disease. The finding that they form molecular memories of certain responses...
Boosting Autophagy in Astrocytes Might Help Cure Alzheimer’s
WEB3 days ago · Boosting autophagy improves amyloid beta clearance. What goes down can come up. When the researchers tried overexpressing the autophagy gene LC3B specifically in astrocytes in Alzheimer’s-prone mice, this significantly decreased the number of amyloid beta plaques in the hippocampus. Boosting autophagy also …
Stanford Medicine study hints at ways to generate new neurons in …
WEB1 day ago · Stanford Medicine News Center 2024 Study hints at ways to generate neurons Story. Stanford Medicine study hints at ways to generate new neurons in old brains share. The researchers’ finding suggests the possibility of designing pharmaceutical or genetic therapies to turn on new neuron production in old or injured brains. October 2, 2024 - By ...
Researchers unveil vital role of astrocytes in mental health
WEBApr 22, 2024 · Astrocytes, as vital cells in the central nervous system, are crucial for brain health and function. Recent research shows that they influence higher cognitive functions and behaviors by...