The arrival of GLP-1 analog drugs (such as Wegovy) marked a huge shift in the weight-loss drug market. These drugs have been shown to lead to significant weight loss in users—as much as 15% or more of their body weight in clinical trials.

At least a dozen experimental weight-loss drugs designed to be taken as pills are working their way through clinical trials, with the most advanced now in the third and final stage of testing.

Weight loss injections are essentially the opposite of pills in terms of pros and cons. They’re generally more effective and there are fewer restrictions around the timing of the dose than pills. They’re typically only taken once per week, which may be an easier schedule to stick to, especially for people who don’t take many medications regularly.

As GLP-1 weight loss drugs fly off shelves, Kourtney Kardashian Barker is getting in on the hustle — well, sort of. As Business Insider and other outlets report, Kardashian Barker's brand Lemme has launched a new line of oral supplements marketed as an alternative to actual glucagon-like peptide-1 drugs like Ozempic and Wegovy.