A new treatment has been proposed for immunotherapy-resistant brain metastases, with a biomarker identified that can predict ...

Researchers at the Spanish National Cancer Research Centre (CNIO) propose a new treatment for brain metastases that respond poorly, or not at all, to immunotherapy, and provide a biomarker to predict ...

Researchers have discovered a new chemical compound, MED6-189, that effectively combats drug-resistant malaria parasites.

Researchers at CNIO discovered that cancer manipulates brain cells called astrocytes, causing them to produce a protein that ...

In brain metastasis, cancer has been found to alter the course of certain astrocytes and causes them to produce a protein that works in the tumor's favor.

A drug called silibinin can block this protein and, when used with immunotherapy, may improve treatment for brain metastases.

Cells around a brain metastasis in an animal model: several brain cells (astrocytes, white) surround an immune system cell (lymphocyte, green). Some of them have started to activate the factor (red) ...

"The pharmacological and genetic modulation of astrocytic autophagy pathway can be considered for boosting the detoxifying ...

Eight other mouse lines were also genotyped as previously described, targeting various cell types and pathways, such as microglia, astrocytes, oligodendrocyte precursor cells, and oligodendrocytes.

The physical and molecular structure of brain tumors has made treatment difficult in the past. The complex nature of the brain frequently makes full surgery challenging, and the blood-tumor barrier ...

Discovery may offer new therapeutic target for development of new drugs against Alzheimer's and other neurodegenerative disorders.