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Long before carriers of autosomal-dominant AD mutations notice the first hints of memory loss, changes in their brains are ...
Hot Spot. GWAS of tau PET scans found a single locus where SNPs (circles) were associated with higher tangle loads. The strongest signal came from SNP rs2113389 (gray diamond). [Courtesy of Nho et al.
The findings indicate that early changes in brain activity—happening in parallel with Aβ and tau accumulation—can predict future cognitive decline. “This suggests that we may be able to detect ...
Driving the Amyloid Cascade? A microglial subtype, Mic.12, promotes plaque deposition, while another, Mic.13, promotes ...
BSc Biomedical Sciences at Lancaster University MSc Neuroscience and Translational Medicine at Queen Mary University of London Now, I'm currently a PhD student at the University of Dundee, looking ...
About two-thirds of people with Alzheimer’s disease are women, yet due to the challenges in studying X chromosomes, a genetic ...